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International Ocean Discovery Program (IODP) Expedition 399 collected new cores from the Atlantis Massif (30°N; Mid-Atlantic Ridge), an oceanic core complex that hosts the Lost City hydrothermal field (LCHF). Studies of the Atlantis Massif and the LCHF have transformed our understanding of tectonic, magmatic, hydrothermal, and microbial processes at slow-spreading ridges. The Atlantis Massif was the site of four previous expeditions (Integrated Ocean Drilling Program Expeditions 304, 305, and 340T and IODP Expedition 357) and numerous dredging and submersible expeditions. The deepest IODP hole in young (<2 My) oceanic lithosphere, Hole U1309D, was drilled ~5 km north of the LCHF and reached 1415 meters below seafloor (mbsf) through a series of primitive gabbroic rocks. A series of 17 shallow (<16.4 mbsf) holes were also drilled at 9 sites across the south wall of the massif during Expedition 357, recovering heterogeneous rock types including hydrothermally altered peridotites, gabbroic, and basaltic rocks. The hydrologic regime differs between the two locations, with a low-permeability conductive regime in Hole U1309D and a high- (and possibly deep-reaching) permeability regime along the southern wall. Expedition 399 targeted Hole U1309D and the southern wall area to collect new data on ancient processes during deformation and alteration of detachment fault rocks. The recovered rocks and fluids are providing new insights into past and ongoing water-rock interactions, processes of mantle partial melting and gabbro emplacement, deformation over a range of temperatures, abiotic organic synthesis reactions, and the extent and diversity of life in the subseafloor in an actively serpentinizing system. We sampled fluids and measured temperature in Hole U1309D before deepening it to 1498 mbsf. The thermal structure was very similar to that measured during Expedition 340T, and lithologies were comparable to those found previously in Hole U1309D. A significant zone of cataclasis and alteration was found at 1451–1474 mbsf. A new Hole U1601C (proposed Site AMDH-02A) was drilled on the southern ridge close to Expedition 357 Hole M0069A, where both deformed and undeformed serpentinites had previously been recovered. Rapid drilling rates achieved a total depth of 1267.8 mbsf through predominantly ultramafic (68%) and gabbroic (32%) rocks, far surpassing the previous drilling record in a peridotite-dominated system of 201 m. Recovery was excellent overall (71%) but particularly high in peridotite-dominated sections where recovery regularly exceeded 90%. The recovery of sizable sections of largely intact material will provide robust constraints on the architecture and composition of the oceanic mantle lithosphere. The deepest portions of the newly drilled borehole may be beyond the known limits of life, providing the means to assess the role of biological activity across the transition from a biotic to an abiotic regime. Borehole fluids from both holes were collected using both the Kuster Flow-Through Sampler and the new Multi-Temperature Fluid Sampler. Wireline logging in Hole U1601C provided information on downhole density and resistivity, imaged structural features, and documented fracture orientations. A reentry system was installed in Hole U1601C, and both it and Hole U1309D were left open for future deep drilling, fluid sampling, and potential borehole observatories. 

Abstract When the scientific dataset evolves or is reused in workflows creating derived datasets, the integrity of the dataset with its metadata information, including provenance, needs to be securely preserved while providing assurances that they are not accidentally or maliciously altered during the process. Providing a secure method to efficiently share and verify the data as well as metadata is essential for the reuse of the scientific data. The National Science Foundation (NSF) funded Open Science Chain (OSC) utilizes consortium blockchain to provide a cyberinfrastructure solution to maintain integrity of the provenance metadata for published datasets and provides a way to perform independent verification of the dataset while promoting reuse and reproducibility. The NSF- and National Institutes of Health (NIH)-funded Neuroscience Gateway (NSG) provides a freely available web portal that allows neuroscience researchers to execute computational data analysis pipeline on high performance computing resources. Combined, the OSC and NSG platforms form an efficient, integrated framework to automatically and securely preserve and verify the integrity of the artifacts used in research workflows while using the NSG platform. This paper presents the results of the first study that integrates OSC–NSG frameworks to track the provenance of neurophysiological signal data analysis to study brain network dynamics using the Neuro-Integrative Connectivity tool, which is deployed in the NSG platform. Database URL: https://www.opensciencechain.org. 

The MicroBooNE experiment is an 85 tonne active mass liquid argon time projection chamber neutrino detector exposed to the on-axis Booster Neutrino Beam at Fermilab. One of MicroBooNE’s physics goals is the precise measurement of neutrino interactions on argon in the 1 GeV energy regime. Building on the capabilities of the MicroBooNE detector, this analysis identifies $K^{+}$mesons, a key signature for the study of strange particle production in neutrino interactions. This measurement is furthermore valuable for background estimation for future nucleon decay searches and for improved reconstruction and particle identification capabilities in experiments such as the Deep Underground Neutrino Experiment. In this Letter, we present the first-ever measurement of a flux-integrated cross section for charged-current muon neutrino induced $K^{+}$production on argon nuclei, determined to be $7.93\pm 3.22\left(\mathrm{stat}\right)\pm 2.83\left(\mathrm{syst}\right)\times {10}^{-42}{\mathrm{cm}}^2/\mathrm{nucleon}$based on an analysis of $6.88\times {10}^{20}$protons on target. This result was found to be consistent with model predictions from different neutrino event generators within the reported uncertainties. 

Abstract The existence of three distinct neutrino flavours,ν_e,ν_μandν_τ, is a central tenet of the Standard Model of particle physics^1,2. Quantum-mechanical interference can allow a neutrino of one initial flavour to be detected sometime later as a different flavour, a process called neutrino oscillation. Several anomalous observations inconsistent with this three-flavour picture have motivated the hypothesis that an additional neutrino state exists, which does not interact directly with matter, termed as ‘sterile’ neutrino,ν_s(refs. ^3–9). This includes anomalous observations from the Liquid Scintillator Neutrino Detector (LSND)³experiment and Mini-Booster Neutrino Experiment (MiniBooNE)^4,5, consistent withν_μ → ν_etransitions at a distance inconsistent with the three-neutrino picture. Here we use data obtained from the MicroBooNE liquid-argon time projection chamber¹⁰in two accelerator neutrino beams to exclude the single light sterile neutrino interpretation of the LSND and MiniBooNE anomalies at the 95% confidence level (CL). Moreover, we rule out a notable portion of the parameter space that could explain the gallium anomaly^6–8. This is one of the first measurements to use two accelerator neutrino beams to break a degeneracy betweenν_eappearance and disappearance, which would otherwise weaken the sensitivity to the sterile neutrino hypothesis. We find no evidence for eitherν_μ → ν_eflavour transitions orν_edisappearance that would indicate non-standard flavour oscillations. Our results indicate that previous anomalous observations consistent withν_μ → ν_etransitions cannot be explained by introducing a single sterile neutrino state. 

We report results from an updated search for neutral current (NC) resonant $\mathrm{\Delta }\left(1232\right)$baryon production and subsequent $\mathrm{\Delta }$radiative decay (NC $\mathrm{\Delta }\to N\gamma$). We consider events with and without final state protons; events with a proton can be compared with the kinematics of a $\mathrm{\Delta }\left(1232\right)$baryon decay, while events without a visible proton represent a more generic phase space. In order to maximize sensitivity to each topology, we simultaneously make use of two different reconstruction paradigms, Pandora and Wire-Cell, which have complementary strengths, and select mostly orthogonal sets of events. Considering an overall scaling of the NC $\mathrm{\Delta }\to N\gamma$rate as an explanation of the MiniBooNE anomaly, our data exclude this hypothesis at 94.4% CL. When we decouple the expected correlations between NC $\mathrm{\Delta }\to N\gamma$events with and without final state protons, our data exclude an interpretation in which all excess events have associated protons at $2.0\sigma$, and are consistent with an interpretation in which all excess events have no associated protons at  $0.63\sigma$. 

We report a new measurement of flux-integrated differential cross sections for charged-current (CC) muon neutrino interactions with argon nuclei that produce no final-state pions ( ${\nu }_{\mu }\mathrm{CC}0\pi$). These interactions are of particular importance as a topologically defined signal dominated by quasielasticlike interactions. This measurement was performed with the MicroBooNE liquid argon time projection chamber detector located at the Fermilab Booster Neutrino Beam and uses an exposure of $1.3\times {10}^{21}$protons on target collected between 2015 and 2020. The results are presented in terms of single- and double-differential cross sections as a function of the final-state muon momentum and angle. The data are compared with widely used neutrino event generators. We find good agreement with the single-differential measurements, while only a subset of generators are also able to adequately describe the data in double-differential distributions. This work facilitates comparison with Cherenkov detector measurements, including those located at the Booster Neutrino Beam.